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Final Programme

Homerton College, Cambridge
6–10 September 2006

Wednesday 6th

15:00–17:00
Registration
17:00–18:20
Welcome Reception
18:20–18:30
Welcome address
J. Greenwood & S. Moss (UK)
Fight for Sight Eye Research logo

1st ISOCB Keynote Lecture

Kindly sponsored by Fight for Sight Eye Research

18:30–19:30
The retinal pigment epithelium: Its role in inherited retinal diseases of the eye
D. Bok (USA)

Thursday 7th

Session 1: Ocular Epithelial Cells I

Chair: Rodriguez-Boulan (USA)

9:00–9:30
Integrin receptor signaling at the RPE-photoreceptor interface
S. Finnemann (USA)
9:30–10:00
Tissue interactions that regulate tight junctions of the RPE
L. J. Rizzolo (USA)
10:00–10:30
Biogenesis and transport of melanosomes and phagosomes in retinal pigment epithelial cells
C. Futter (UK)
10:30–11:00
Coffee

Session 2: Lens and Vitreous

Chair: M. Bailly (UK)

11:00–11:30
Connexin specialization in lens cell growth and differentiation
T. White (USA)
11:30–12:00
The optical properties of the lens requires a functional cytoskeleton
R. Quinlan (UK)
12:00–12:30
The anti-angiogenic properties of opticin
P. Bishop (UK)
12:30–13:30
Lunch
The Physiological Society (UK)

Session 3: Retinal Development I

Chair: P. E. Rakoczy (AUS)

13:30–14:00
Time lapse analysis of cellular development in the retina
W. Harris (UK)
14:00–14:30
The Order of Cell Genesis in the Vertebrate Retina is Extremely Precise: A Clonal Analysis of Cell Birthdays
D. Rapaport (USA)
14:30–15:00
The formation of cellular mosaics in the retina
L. Galli-Resta (Italy)
15:00–15:30
Tea
The Physiological Society (UK)

Session 4: Retinal Development II

Chair: W. Harris (UK)

15:30–16:00
The formation of dendritic coverage and connectivity in the retina
B. Reese (USA)
16:00–16:30
Imaging circuit assembly in the vertebrate retina
R. Wong (UK)
16:30–17:00
The role of acetylcholine, GABA and visual experience in controlling the development of retinal circuitry
E. Sernagor (UK)
17:00–18:30
Thursday's poster session

Friday 8th

Session 1: Photoreceptors I

Chair: to be confirmed

9:30–9:30
Molecular chaperones and photoreceptor function
M. Cheetham (UK)
9:30–10:00
Proteomic analysis of rod outer segments
Dr Robert Molday (Canada)
10:00–10:30
The maintenance and death of the mammalian photoreceptor (PR)
R. McInnes (Canada)
10:30–11:00
Coffee
ReNeuron

Session 2: Stem Cells

Chair: E. Miljan (UK)

11:00–11:30
Molecular chaperones and photoreceptor function
M. Cheetham (UK)
11:30–12:00
Proteomic analysis of rod outer segments
Dr Robert Molday (Canada)
12:00–12:30
The maintenance and death of the mammalian photoreceptor (PR)
R. McInnes (Canada)
12:30–13:30
Lunch
Oxford BioMedica

Session 3: Ocular Cell Dysfunction I

Chair: I. Grierson (UK)

13:30–14:00
Aberrant lipid metabolism and dietary intervention: Consequences to retinal structure, function, and steady-state composition
S. Fliesler (USA)
14:00–14:30
Oxidative damage and cone cell death in primary rod cell degenerations
P. A. Campochiaro (USA)
14:30–15:00
Rab GTPases in the retina and relevance to retinal degenerations
M. Seabra (UK)
15:00–15:30
Tea

Session 4: Therapy

Chair: G. Hageman (USA)

15:30–16:00
Bringing Cell and Pharmaceutical Therapy into the Clinic
J. Sahel (France)
16:00–16:30
Regenerating the diseased eye using human embryonic stem cells
Dr Peter Coffey (UK)
16:30–17:00
From repair to regeneration: New treatments from the laboratory
P. Khaw (UK)
17:00–18:30
Friday's poster session

Saturday 9th

Session 1: Ocular Endothelial Cells

Chair: J. Greenwood (UK)

9:00–9:30
VEGFRI is a critical regulator of ocular angiogenesis
M. Boulton (UK)
9:30–10:00
Modulation of paracellular permeability in retinal vascular endothelial cells
P. Turowski (UK)
10:30–10:30
Development of the mouse retinal vasculature
M. Fruttiger (UK)
10:30–11:00
Coffee

Session 2: Retina

Chair: M. Cheethman (UK)

11:00–11:30
Photoreceptive retinal ganglion cells (pRGCs): Emerging roles and photosensory mechanisms
R. G. Foster (UK)
11:30–12:00
Biochemical mechanisms of visual pigment regeneration in the vertebrate retina
G. H. Travis (USA)
12:00–12:30
Vesicle recycling at the ribbon synapse of bipolar cells
L. Lagnado (UK)
12:30–13:30
Lunch

Session 3: Ocular Epithelial Cells II

Chair: D. Bok (UK)

13:00–14:00
Control of epthelial cell dynamics on the ocular surface
M. E. Fini (USA)
14:00–14:30
Differentiation of the RPE: The role of the tight junctions
M. Balda (UK)
14:30–15:00
Identification of proteins involved in RPE phagocytosis
D. Vollrath (USA)
15:00–15:30
Tea

Session 4: Photoreceptors II

Chair: D. Williams

15:30–16:00
The role of the Usher protein network in photoreceptor cell function
U. Wolfrum (Germany)
16:00–16:30
Hyaluronan and the functional organization of the interphotoreceptor matrix
J. G. Hollyfield (USA)
16:30–17:00
Light-driven protein translocation between the major subcellular compartments of photoreceptors
V. Arshavsky (USA)
15:00–15:30
Saturday's poster session

Sunday 10th

Session 1: Ocular Cell Dysfunction II

Chair: J. Usukura (Japan)

9:00–9:30
Growth factor-mediated actin dynamics and mechanical force generation during ocular scarring
M. Bailly (UK)
9:30–10:00
Lysosomal dysfunction of the RPE: A key event in the pathogenesis of ARMD?
J. Kopitz (Germany)
10:30–10:30
The role of rhodopsin in signaling and disease
J. Chen (USA)
10:30–11:00
Coffee

Session 2: Complement Factor H

Chair: S. E. Moss (UK)

11:00–11:30
Complement Factor H and its interaction with zinc - A structural view
S. Perkins (UK)
11:30–12:00
Role of the complement pathway in age-related macular degeneration
G. Hageman (USA)
12:00–12:30
Retinal function in the Complement Factor H knock-out mouse
P. Luthert (UK)
–
Close of meeting